René Bruno is currently Staff Scientist in Clinical Pharmacology at Genentech Research and Early Development (gRED) based France. He provides scientific leadership in the development and application of Modeling and Simulation (M&S) in drug development, with a special focus in oncology and immuno-oncology supporting various early and late stage projects. René has more than 30 years of experience in academia, industry, and consulting business, including University of Marseilles, Syntex, Rhone-Poulenc Rorer, and Genentech. In the most recent 13 years before coming back to Genentech in June 2016, René was Managing Director in Pharsight/Certara Consulting Services where he provided Modeling and Simulation (M&S) consultation for leading pharmaceutical companies worldwide.
René specific research interest has been in oncology tumor growth inhibition modeling, including linking tumor response to outcomes data such as Overall Survival, and application of these models to trial design and development decisions. He has published 65+ peer-reviewed research articles, 16+ invited book chapters, reviews, and commentaries, and delivered 50+ invited lectures at global scientific conferences and universities. René is one of the founding members for PAGE and hosted for the 1st meeting in 1993 in Paris. Rene is currently the president of the International Society of Pharmacometrics (ISoP).